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Testing for disease?

Genetic screening of embryos using the techniques of sperm selection and PGD are sophisticated ways to avoid a growing number of genetic diseases but they have provoked many ethical arguments.


An embryo a few days old

In the United States a deaf lesbian couple has intentionally had two deaf children by artificial insemination using sperm from a man who had a long family history of deafness. This couple deliberately chose to bring a child into the world with a disability. This sort of choice raises new ethical issues.

Scientists are learning more and more about how genes work and interact with each other. Using PGD it will soon be possible to screen and select for many more diseases. In the future it may be possible to really create 'designer babies' and to move from testing for medical conditions to the selection of designer features such as height, eye colour, facial appearance and perhaps even intelligence and personality.


Designer baby or just healthy baby

The success of PGD has shifted scientists' attention away from germ line therapy, which is the attempt to alter the genes in eggs, sperm or embryos. Increasingly, parents can avoid passing a faulty gene on to their child using this type of genetic screening.

In 2000, in the United States, the Nash family made medical history by having a baby boy who had been selected using PGD to be a perfect tissue match for his very ill older sister. His sister suffered from a rare genetic disease so tissue from her new-born brother's placenta was used to restore her to health. The same thing was allowed to occur in 2001 in the UK and now many more parents are applying to the authorities for permission to do the same thing.


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